R64L (p.Arg64Leu) variant of CYP2A6 (Cytochrome P450 2A6)
R64L (p.Arg64Leu) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
R64L (p.Arg64Leu) variant details
- p.Arg64Leu
- ESP rs374515279
- ExAC rs374515279
- TOPMed rs374515279
- gnomAD rs374515279
- Missense
- Variant Prioritization Score for Impact Estimate 0.161
- REVEL 0.11
- CADD 0.01
- PolyPhen-2 0.11
- SIFT 0.06
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available