R27G (p.Arg27Gly) variant of CYP2A6 (Cytochrome P450 2A6)
R27G (p.Arg27Gly) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
R27G (p.Arg27Gly) variant details
- p.Arg27Gly
- 1000Genomes rs563981730
- ExAC rs563981730
- TOPMed rs563981730
- gnomAD rs563981730
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.11
- CADD 14.50
- PolyPhen-2 0.02
- SIFT 0.19
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available