P67S (p.Pro67Ser) variant of CYP2A6 (Cytochrome P450 2A6)
P67S (p.Pro67Ser) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
P67S (p.Pro67Ser) variant details
- p.Pro67Ser
- ExAC rs745654874
- TOPMed rs745654874
- gnomAD rs745654874
- Missense
- Variant Prioritization Score for Impact Estimate 0.0978
- REVEL 0.07
- CADD 0.27
- PolyPhen-2 0.32
- SIFT 0.14
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available