P37A (p.Pro37Ala) variant of CYP2A6 (Cytochrome P450 2A6)
P37A (p.Pro37Ala) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
P37A (p.Pro37Ala) variant details
- p.Pro37Ala
- ExAC rs766052140
- TOPMed rs766052140
- gnomAD rs766052140
- Missense
- Variant Prioritization Score for Impact Estimate 0.43
- REVEL 0.21
- CADD 23.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available