P35R (p.Pro35Arg) variant of CYP2A6 (Cytochrome P450 2A6)
P35R (p.Pro35Arg) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
P35R (p.Pro35Arg) variant details
- p.Pro35Arg
- ESP rs377713545
- ExAC rs377713545
- TOPMed rs377713545
- gnomAD rs377713545
- Missense
- Variant Prioritization Score for Impact Estimate 0.38
- REVEL 0.19
- CADD 23.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Ashkenazi Jewish population (allele frequency 0.0014)
- Structural context available