M18I (p.Met18Ile) variant of CYP2A6 (Cytochrome P450 2A6)
M18I (p.Met18Ile) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
M18I (p.Met18Ile) variant details
- p.Met18Ile
- Ensembl rs1967200007
- Missense
- Variant Prioritization Score for Impact Estimate 0.226
- REVEL 0.07
- CADD 10.90
- PolyPhen-2 0.00
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available