L91V (p.Leu91Val) variant of CYP2A6 (Cytochrome P450 2A6)
L91V (p.Leu91Val) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
L91V (p.Leu91Val) variant details
- p.Leu91Val
- TOPMed rs1303229628
- gnomAD rs1303229628
- Missense
- Variant Prioritization Score for Impact Estimate 0.505
- REVEL 0.52
- CADD 22.00
- PolyPhen-2 0.94
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available