K60N (p.Lys60Asn) variant of CYP2A6 (Cytochrome P450 2A6)
K60N (p.Lys60Asn) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
K60N (p.Lys60Asn) variant details
- p.Lys60Asn
- TOPMed rs1967196834
- gnomAD rs1967196834
- Missense
- Variant Prioritization Score for Impact Estimate 0.522
- REVEL 0.31
- CADD 33.00
- PolyPhen-2 0.88
- SIFT 0.07
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available