K32R (p.Lys32Arg) variant of CYP2A6 (Cytochrome P450 2A6)
K32R (p.Lys32Arg) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
K32R (p.Lys32Arg) variant details
- p.Lys32Arg
- gnomAD rs1259313052
- Missense
- Variant Prioritization Score for Impact Estimate 0.106
- REVEL 0.01
- CADD 0.07
- PolyPhen-2 0.01
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available