K32N (p.Lys32Asn) variant of CYP2A6 (Cytochrome P450 2A6)
K32N (p.Lys32Asn) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
K32N (p.Lys32Asn) variant details
- p.Lys32Asn
- gnomAD rs1967198800
- Missense
- Variant Prioritization Score for Impact Estimate 0.142
- REVEL 0.03
- CADD 4.35
- PolyPhen-2 0.05
- SIFT 0.12
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available