I71T (p.Ile71Thr) variant of CYP2A6 (Cytochrome P450 2A6)
I71T (p.Ile71Thr) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
I71T (p.Ile71Thr) variant details
- p.Ile71Thr
- TOPMed rs1967190096
- Missense
- Variant Prioritization Score for Impact Estimate 0.43
- REVEL 0.38
- CADD 23.30
- PolyPhen-2 0.68
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available