I71F (p.Ile71Phe) variant of CYP2A6 (Cytochrome P450 2A6)
I71F (p.Ile71Phe) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
I71F (p.Ile71Phe) variant details
- p.Ile71Phe
- TOPMed rs2072079798
- Missense
- Variant Prioritization Score for Impact Estimate 0.148
- REVEL 0.22
- CADD 1.78
- PolyPhen-2 0.05
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available