I61N (p.Ile61Asn) variant of CYP2A6 (Cytochrome P450 2A6)
I61N (p.Ile61Asn) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
I61N (p.Ile61Asn) variant details
- p.Ile61Asn
- ExAC rs776709300
- gnomAD rs776709300
- Missense
- Variant Prioritization Score for Impact Estimate 0.412
- REVEL 0.28
- CADD 24.30
- PolyPhen-2 0.82
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available