I61F (p.Ile61Phe) variant of CYP2A6 (Cytochrome P450 2A6)
I61F (p.Ile61Phe) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
I61F (p.Ile61Phe) variant details
- p.Ile61Phe
- ExAC rs200554095
- gnomAD rs200554095
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.19
- CADD 0.04
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the HGDP:BERGAMOITALIAN population (allele frequency 0.045)
- Structural context available