G83R (p.Gly83Arg) variant of CYP2A6 (Cytochrome P450 2A6)
G83R (p.Gly83Arg) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
G83R (p.Gly83Arg) variant details
- p.Gly83Arg
- ExAC rs757073282
- gnomAD rs757073282
- Missense
- Variant Prioritization Score for Impact Estimate 0.454
- REVEL 0.33
- CADD 23.60
- PolyPhen-2 0.94
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available