G36V (p.Gly36Val) variant of CYP2A6 (Cytochrome P450 2A6)
G36V (p.Gly36Val) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
G36V (p.Gly36Val) variant details
- p.Gly36Val
- TOPMed rs558145012
- Missense
- Variant Prioritization Score for Impact Estimate 0.519
- REVEL 0.36
- CADD 22.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available