G36A (p.Gly36Ala) variant of CYP2A6 (Cytochrome P450 2A6)
G36A (p.Gly36Ala) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
G36A (p.Gly36Ala) variant details
- p.Gly36Ala
- TOPMed rs558145012
- Missense
- Variant Prioritization Score for Impact Estimate 0.466
- REVEL 0.27
- CADD 22.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available