G31R (p.Gly31Arg) variant of CYP2A6 (Cytochrome P450 2A6)
G31R (p.Gly31Arg) in CYP2A6 (Cytochrome P450 2A6) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
G31R (p.Gly31Arg) variant details
- p.Gly31Arg
- NCI-TCGA Cosmic COSV1043
- TOPMed rs1967198875
- gnomAD rs1967198875
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.205
- REVEL 0.04
- CADD 6.83
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available