F118Y (p.Phe118Tyr) variant of CYP2A6 (Cytochrome P450 2A6)
F118Y (p.Phe118Tyr) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
F118Y (p.Phe118Tyr) variant details
- p.Phe118Tyr
- ExAC rs763988737
- gnomAD rs763988737
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- REVEL 0.33
- CADD 24.00
- PolyPhen-2 0.74
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available