E63G (p.Glu63Gly) variant of CYP2A6 (Cytochrome P450 2A6)
E63G (p.Glu63Gly) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
E63G (p.Glu63Gly) variant details
- p.Glu63Gly
- gnomAD rs1242615648
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.14
- CADD 21.50
- PolyPhen-2 0.03
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available