A10T (p.Ala10Thr) variant of CYP2A6 (Cytochrome P450 2A6)
A10T (p.Ala10Thr) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
A10T (p.Ala10Thr) variant details
- p.Ala10Thr
- TOPMed rs1967200742
- Missense
- Variant Prioritization Score for Impact Estimate 0.212
- REVEL 0.07
- CADD 4.60
- PolyPhen-2 0.00
- SIFT 0.42
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available