A105V (p.Ala105Val) variant of CYP2A6 (Cytochrome P450 2A6)
A105V (p.Ala105Val) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
A105V (p.Ala105Val) variant details
- p.Ala105Val
- ExAC rs754143940
- gnomAD rs754143940
- Missense
- Variant Prioritization Score for Impact Estimate 0.416
- REVEL 0.20
- CADD 22.90
- PolyPhen-2 0.89
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available