R26W (p.Arg26Trp) variant of CYP21A2 (Steroid 21-hydroxylase)
R26W (p.Arg26Trp) in CYP21A2 (Steroid 21-hydroxylase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
R26W (p.Arg26Trp) variant details
- p.Arg26Trp
- ExAC rs749346869
- TOPMed rs749346869
- gnomAD rs749346869
- Missense
- Variant Prioritization Score for Impact Estimate 0.0771
- CADD 3.23
- PolyPhen-2 0.01
- SIFT 0.15
- Most common in the Middle Eastern population (allele frequency 0.00018)
- Structural context available