P11S (p.Pro11Ser) variant of CYP21A2 (Steroid 21-hydroxylase)
P11S (p.Pro11Ser) in CYP21A2 (Steroid 21-hydroxylase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
P11S (p.Pro11Ser) variant details
- p.Pro11Ser
- ExAC rs764653902
- TOPMed rs764653902
- gnomAD rs764653902
- Missense
- Variant Prioritization Score for Impact Estimate 0.0687
- CADD 1.73
- PolyPhen-2 0.01
- SIFT 0.25
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available