W26C (p.Trp26Cys) variant of CYP1A2 (Cytochrome P450 1A2)
W26C (p.Trp26Cys) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
W26C (p.Trp26Cys) variant details
- p.Trp26Cys
- gnomAD 15-74749816-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.484
- REVEL 0.42
- CADD 24.00
- PolyPhen-2 1.00
- SIFT 0.04
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available