V7F (p.Val7Phe) variant of CYP1A2 (Cytochrome P450 1A2)
V7F (p.Val7Phe) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
V7F (p.Val7Phe) variant details
- p.Val7Phe
- gnomAD 15-74749757-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0948
- REVEL 0.10
- CADD 4.30
- PolyPhen-2 0.28
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available