T56A (p.Thr56Ala) variant of CYP1A2 (Cytochrome P450 1A2)
T56A (p.Thr56Ala) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
T56A (p.Thr56Ala) variant details
- p.Thr56Ala
- gnomAD rs1378709714
- Missense
- Variant Prioritization Score for Impact Estimate 0.206
- REVEL 0.10
- CADD 22.80
- PolyPhen-2 0.36
- SIFT 0.05
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available