R67K (p.Arg67Lys) variant of CYP1A2 (Cytochrome P450 1A2)
R67K (p.Arg67Lys) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
R67K (p.Arg67Lys) variant details
- p.Arg67Lys
- gnomAD 15-74749938-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.126
- REVEL 0.17
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.59
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available
- Literature evidence available