R67G (p.Arg67Gly) variant of CYP1A2 (Cytochrome P450 1A2)
R67G (p.Arg67Gly) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
R67G (p.Arg67Gly) variant details
- p.Arg67Gly
- ExAC rs760996321
- gnomAD rs760996321
- Missense
- Variant Prioritization Score for Impact Estimate 0.22
- REVEL 0.32
- CADD 4.16
- PolyPhen-2 0.25
- SIFT 0.11
- Most common in the Ashkenazi Jewish population (allele frequency 0.00011)
- Structural context available