R34W (p.Arg34Trp) variant of CYP1A2 (Cytochrome P450 1A2)
R34W (p.Arg34Trp) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
R34W (p.Arg34Trp) variant details
- p.Arg34Trp
- 1000Genomes rs201934979
- ESP rs201934979
- TOPMed rs201934979
- gnomAD rs201934979
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.07
- CADD 15.80
- PolyPhen-2 0.03
- SIFT 0.03
- Most common in the 1KG:CEU population (allele frequency 0.0042)
- Structural context available