R32K (p.Arg32Lys) variant of CYP1A2 (Cytochrome P450 1A2)
R32K (p.Arg32Lys) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
R32K (p.Arg32Lys) variant details
- p.Arg32Lys
- TOPMed rs1244631935
- gnomAD rs1244631935
- Missense
- Variant Prioritization Score for Impact Estimate 0.064
- REVEL 0.06
- CADD 1.55
- PolyPhen-2 0.01
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available