Q5L (p.Gln5Leu) variant of CYP1A2 (Cytochrome P450 1A2)
Q5L (p.Gln5Leu) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
Q5L (p.Gln5Leu) variant details
- p.Gln5Leu
- TOPMed rs2063304716
- Missense
- Variant Prioritization Score for Impact Estimate 0.0835
- REVEL 0.07
- CADD 6.98
- PolyPhen-2 0.01
- SIFT 0.21
- Most common in the Latino/Admixed American population (allele frequency 2.8e-05)
- Structural context available