P8T (p.Pro8Thr) variant of CYP1A2 (Cytochrome P450 1A2)
P8T (p.Pro8Thr) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
P8T (p.Pro8Thr) variant details
- p.Pro8Thr
- gnomAD 15-74749760-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.154
- REVEL 0.11
- CADD 9.02
- PolyPhen-2 0.38
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available