P61L (p.Pro61Leu) variant of CYP1A2 (Cytochrome P450 1A2)
P61L (p.Pro61Leu) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
P61L (p.Pro61Leu) variant details
- p.Pro61Leu
- ExAC rs761818825
- TOPMed rs761818825
- gnomAD rs761818825
- Missense
- Variant Prioritization Score for Impact Estimate 0.601
- REVEL 0.50
- CADD 24.80
- PolyPhen-2 1.00
- SIFT 0.03
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available