P36S (p.Pro36Ser) variant of CYP1A2 (Cytochrome P450 1A2)
P36S (p.Pro36Ser) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
P36S (p.Pro36Ser) variant details
- p.Pro36Ser
- ESP rs146974121
- ExAC rs146974121
- TOPMed rs146974121
- gnomAD rs146974121
- Missense
- Variant Prioritization Score for Impact Estimate 0.508
- REVEL 0.45
- CADD 24.40
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 0.00012)
- Structural context available