P36L (p.Pro36Leu) variant of CYP1A2 (Cytochrome P450 1A2)
P36L (p.Pro36Leu) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
P36L (p.Pro36Leu) variant details
- p.Pro36Leu
- gnomAD rs1174406258
- Missense
- Variant Prioritization Score for Impact Estimate 0.474
- REVEL 0.44
- CADD 23.50
- PolyPhen-2 1.00
- SIFT 0.07
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available