P33S (p.Pro33Ser) variant of CYP1A2 (Cytochrome P450 1A2)
P33S (p.Pro33Ser) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data, published literature, and structural context.
P33S (p.Pro33Ser) variant details
- p.Pro33Ser
- gnomAD 15-74749835-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0589
- REVEL 0.05
- CADD 0.01
- PolyPhen-2 0.28
- SIFT 0.75
- Most common in the Non-Finnish European population (allele frequency 7.2e-06)
- Structural context available
- Literature evidence available