P33R (p.Pro33Arg) variant of CYP1A2 (Cytochrome P450 1A2)
P33R (p.Pro33Arg) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
P33R (p.Pro33Arg) variant details
- p.Pro33Arg
- ExAC rs775486408
- gnomAD rs775486408
- Missense
- Variant Prioritization Score for Impact Estimate 0.206
- REVEL 0.17
- CADD 13.30
- PolyPhen-2 0.58
- SIFT 0.39
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available