L65P (p.Leu65Pro) variant of CYP1A2 (Cytochrome P450 1A2)
L65P (p.Leu65Pro) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
L65P (p.Leu65Pro) variant details
- p.Leu65Pro
- ESP rs71651689
- ExAC rs71651689
- TOPMed rs71651689
- gnomAD rs71651689
- Missense
- Variant Prioritization Score for Impact Estimate 0.779
- REVEL 0.90
- CADD 25.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 5e-05)
- Structural context available