L65M (p.Leu65Met) variant of CYP1A2 (Cytochrome P450 1A2)
L65M (p.Leu65Met) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
L65M (p.Leu65Met) variant details
- p.Leu65Met
- gnomAD 15-74749931-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.528
- REVEL 0.54
- CADD 23.00
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available