L63P (p.Leu63Pro) variant of CYP1A2 (Cytochrome P450 1A2)
L63P (p.Leu63Pro) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
L63P (p.Leu63Pro) variant details
- p.Leu63Pro
- gnomAD 15-74749926-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.563
- REVEL 0.63
- CADD 26.40
- PolyPhen-2 0.98
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available