L51F (p.Leu51Phe) variant of CYP1A2 (Cytochrome P450 1A2)
L51F (p.Leu51Phe) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
L51F (p.Leu51Phe) variant details
- p.Leu51Phe
- ExAC rs745706596
- TOPMed rs745706596
- gnomAD rs745706596
- Missense
- Variant Prioritization Score for Impact Estimate 0.204
- REVEL 0.18
- CADD 12.00
- PolyPhen-2 0.03
- SIFT 0.02
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available