L3F (p.Leu3Phe) variant of CYP1A2 (Cytochrome P450 1A2)
L3F (p.Leu3Phe) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
L3F (p.Leu3Phe) variant details
- p.Leu3Phe
- ExAC rs758501844
- gnomAD rs758501844
- Missense
- Variant Prioritization Score for Impact Estimate 0.218
- REVEL 0.05
- CADD 1.55
- PolyPhen-2 0.03
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9.4e-07)
- Structural context available