L39P (p.Leu39Pro) variant of CYP1A2 (Cytochrome P450 1A2)
L39P (p.Leu39Pro) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
L39P (p.Leu39Pro) variant details
- p.Leu39Pro
- gnomAD 15-74749854-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.365
- REVEL 0.39
- CADD 25.20
- PolyPhen-2 0.99
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available