L39M (p.Leu39Met) variant of CYP1A2 (Cytochrome P450 1A2)
L39M (p.Leu39Met) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
L39M (p.Leu39Met) variant details
- p.Leu39Met
- gnomAD 15-74749853-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.17
- CADD 22.70
- PolyPhen-2 0.59
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available