L23V (p.Leu23Val) variant of CYP1A2 (Cytochrome P450 1A2)
L23V (p.Leu23Val) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
L23V (p.Leu23Val) variant details
- p.Leu23Val
- gnomAD 15-74749805-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.373
- REVEL 0.31
- CADD 15.60
- PolyPhen-2 0.84
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available