L23Q (p.Leu23Gln) variant of CYP1A2 (Cytochrome P450 1A2)
L23Q (p.Leu23Gln) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
L23Q (p.Leu23Gln) variant details
- p.Leu23Gln
- gnomAD 15-74749806-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.55
- REVEL 0.61
- CADD 24.90
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available