L23M (p.Leu23Met) variant of CYP1A2 (Cytochrome P450 1A2)
L23M (p.Leu23Met) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
L23M (p.Leu23Met) variant details
- p.Leu23Met
- gnomAD 15-74749805-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.436
- REVEL 0.42
- CADD 16.50
- PolyPhen-2 0.99
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available