L16P (p.Leu16Pro) variant of CYP1A2 (Cytochrome P450 1A2)
L16P (p.Leu16Pro) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
L16P (p.Leu16Pro) variant details
- p.Leu16Pro
- gnomAD 15-74749785-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.595
- REVEL 0.65
- CADD 25.20
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available