L15F (p.Leu15Phe) variant of CYP1A2 (Cytochrome P450 1A2)
L15F (p.Leu15Phe) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
L15F (p.Leu15Phe) variant details
- p.Leu15Phe
- 1000Genomes rs60086777
- ESP rs60086777
- ExAC rs60086777
- TOPMed rs60086777
- Missense
- Variant Prioritization Score for Impact Estimate 0.44
- REVEL 0.49
- CADD 21.80
- PolyPhen-2 0.98
- SIFT 0.05
- Most common in the HGDP:SINDHI population (allele frequency 0.045)
- Structural context available